• (of a task, problem, etc.) Thorny; difficult to deal with, especially due to being complex or tricky.

    "Be careful what you say to him; he's a nettlesome fellow."

  • "The task of proving Fermat’s “last” theorem remains nettlesome."

  • (of a person, thing, situation, etc.) Causing irritation, annoyance, or discomfort; bothersome, irksome.

    "My poison ivy rash is very nettlesome."

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